catbirdseat

My old boss, Dave D., was in the research group at UW that elucidated the mechanism of acetaminophen liver toxicity. A highly reactive benzoquinone species forms. It is very hard to observe because of the reactivity. It was trapped by reacting with another molecule and it's existence inferred. Liver failure is a real bummer. Don't mess around with Tylenol and alcohol. Regarding Aspirin versus Naproxen. I read somewhere that Aspirin is a 4000:1 COX-1/ COX-2 inhibitor, which explains why it is so harsh on the stomach. The prostaglandins that COX-1 produces are protective of the stomach lining. Naproxen is 1:1 COX-1/COX-2. This is the lowest ratio of all the over the counter NSAIDS.

That sucks the Great Green Weenie.

They should have named it Holy Grail Pale Ale, not Stale!

But he staggers creatively and with great literary skill.

You are probably right. I Forester could probably do it, but not an Outback or a Legacy Wagon. I know this place that would be such an incredible place to car camp and have a party. Views of Rainier, Adams and Stuart. Have a kegger and watch the sunset.

The Beckey Route ordinarily isn't worth reading about, but do it in the snow in mountain boots and it can be interesting. All depends on what happened and how you wrote it up. Uncle Tricky could write a great TR about walking to the corner store to buy a carton of milk.

Lyrics by Mark Murphy to Dat Dere, by Thelonius Monk Hey Daddy what's a square? And where do we get air? And Daddy, oh hey Daddy what and why and where? Hey Daddy what dat dere? And what dey doing dere? And Daddy can I have that big elephant over there?

Dru you should kiss the ground Uncle Tricky walks on, rather than sully it the way you do.

Forget about who said it for once and address what he said goddamit! You get so wrapped up in labeling people. Either you agree with the statement or you don't!

That's great!

Moose Drool is thick and so is the beer.

As heard on NPR. Table Saw Technology Aims to Save Fingers.

I like his stuff. Nobody else has creativity to match this morning.

Oh, brother, I've had it for 5 weeks now. I went to get a chest x-ray yesterday because my doc was worried it might be TB. It's not. It's bronchitis. I'm so tired of coughing.

Try the Old Durr Road out by Ellensburg. It transits both Manashtash and Umtanum Ridges. It's pretty cool.

Bad cough and a stomach ache.

Monitor the Events Forum for Pube Club 12/14, and hopefully Dave will get it organized.

It's a cat. Elizabethan? Where's the ruff?

RobBob, will you be in town on Tuesday? If so, a stop at Pub Club is mandatory.

baddabing!

...and keep it wrapped it up, me bucko mate.

This was supposed to be the thread that would bring all the hot chicks out of the woodwork. But we get you queers instead. I am soooo disappointed.

It's YOU'RE as in YOU ARE, retard.

Wow, Jason, that is a cool article. I think everyone should read it. The guy has some amazing insight.

Oh, lordy, I've done the 50 year old glavanized steel plumbing thing. Yuck. I finally ripped it all out and put in copper. I still hate crawl spaces. Muffy do you like cobwebs and spiders?