billcoe

I spent three years back in the 1980's working on a Parkinson's drug at drug research company in Irvine (N-0923). Nineteen years after it was discovered, the drug was finally FDA approved in 2007 by a successor company under the generic name of Rotigotine. It is now in clinical trials for a different indication- "restless leg syndrome". The drug is a dopamine D2 agonist. It's very potent and is delivered by a patch. Interestingly, we tested it in rats to discover if it was habit forming. The result was that it is three times more addictive than cocaine when administered intravenously. You won't get any of this information by looking it up in Wikipedia. ;-) Whoa......speechless.

Not me Andrew, but sometimes it seems that you're a little hard on The Beaver.

JB, I had you covered 10 posts up (quoted post below). Thank you for the great posts lately on multiple threads - some great quality information. I reposted your conclusion as it was a perfect summation. I suppose I could have bolded the text and added an exclamation point for Jayb but he's a real sharp guy and I figured your post stood well on its own. Good stuff dude, thank you.

Still a classic but I thought we'd all moved on past this embarrassing moment, is round 2 coming up... what? How did the thread take a left turn?

Damn, it almost makes you support Islamic justice.

2 days of climbing followed by a 3 or 4 mile death march with my wife on an urban trail. I tryed to carry extra water for ballast, thinking I could out hike her like always. Shes been training regularly on trail hiking and running and she ground me into the dust. ______________________________________________________________ No CBS, only the rare Ibuprofen but I did just polish off a full mason quart jar of Ujahns homebrew, a deep chocolate stout...ummmmmm that stuff is soo goooood. I have 3 swallows left and then it's time to pee....and that's another thing (spoken like Andy Rooney).... Drained it ahhhhhhhh

And yet you showed up and then contributed less than Kevin E-rock...hmmmm interesting. Bone, you and I are close to agreeing here. It is wrong to hold people, many on flimsy if any evidence, indefinitely. It goes against what our country stands for and what makes us strong. Give them a trial or set them free. The difference is that most of these are POWs, battlefield warriors who were captured. Imagine if in WW2, the US had tried all of the captured German troops. What would the charge have been anyway? How would you provide evidence? It can't be processed that way. However, it should have been processed via tribunal by now, and the real badasses locked up or hung and the rest let go. In a sense, that has been occurring at a glacial pace.

Well spoken as always Jayb. I'm even willing to give folks who want to spew that the nutritional value is higher the benefit of the doubt. Frankly, I remember buying some organic Oranges at natures once, that tasted so good that my kids and I ate them all and immediately went back and bought another sack most of which we ate immediately. The taste was so significantly better it would be hard not to believe it to have more nutrients than the nearly unpalatable bland cardboard masquerading as oranges at the Safeway store. If someone cannot separate taste and nutritional content, I can live with it. Like you, what ever floats folks boats. I think separating out the various health risks of organic or not as it relates to food may be the more prudent approach. Antibiotics, for example, may have different health risks than growth Hormones and pesticides, and it seems clear that there are huge and widespread health issues in the process of cropping up from this practice. Here's some links of scientific consensus starting to form. Perhaps the evidence is less than startling conclusive, yet if you could avoid unwanted antibiotics from possibly screwing up our children, wouldn't you want that? New England Journal of Medicine articals www.cals.ncsu.edu/waste_mgt/natlcenter/sanantonio/Ohl.ppt http://www.pbs.org/wgbh/pages/frontline/shows/meat/safe/overview.html opps, looks like my 2nd link, which is a powerpoint presentation, didn't take and will be cut and past for you. Here are the abstracts for anyone to look up. * White DG, Zhao S, Suler R et al. The isolation of antibiotic-resistant salmonella from retail ground meats. N Engl J Med 2001;345:1147-54. Abstract * McDonald LC, Rossiter S, Mackinson C et al. Quinupristin-Dalfopristin-Resistant Enterococcus faecium on Chicken and in Human Stool Specimens. N Engl J Med 2001;345:1155-60. Abstract * Sørensen TL, Blom M, Monnet DL et al. Transient Intestinal Carriage after Ingestion of Antibiotic-Resistant Enterococcus faecium from Chicken and Pork. N Engl J Med 2001;345:1161-6. Abstract

If they are not terrorists they can let them go, if they are terrorists, they can hold them there as well as hold them inside the US border. If they are going to have a tribunal why not there? How much do you think this move will cost? What will it really do? IMO It's just expensive window dressing that will do nothing and cost you money. Stupid.

Yeah, that's what I did. Walked in to the Michael Jackson memorial medicine cabinet, ate some vitamin I, typed for a bit and went back to bed and slept like a baby. Like a baby this time wasn't = cryed all night and peed myself. LOL

Woke up @2-3am the last 2 days with muscles so sore that I can't sleep nor can I get back to sleep. This never use to happen when I was a pup. Wonder how Becky manages at his age, its nothing short of astounding to me. Nothing else happening...take care all.

For Don:

They all haven't been disingenuous. As people note above, your study doesn't include pesticide, hormone, antibiotics and other harmful things that are excluded from organic foods. I appreciate that our food production is world class. You can't get that kind of production without large amounts of pesticides, herbicides and scientific study. Frankly, the mainstream food we eat has been studied extensively and found to be generally safe to eat as we buy it from mainstream markets - yet that doesn't make it conclusive at all that pesticide use is good for you. Some organics have their own set of unsafe issues as well, they aren't always better, especially as it pertains to unpasturized milk and milk products like cheese. Antibiotic research coming to light seems to be indicating that blanket application in livestock will lead to transfer to humans, then causing them to be allergic to antibiotics and/or antibiotic resistant stains of disease occurring, and it ain't a good thing. To lump organic as a waste because the nutrition value, and that alone is the same, while ignoring every other bit of data on these other issues seems disingenuous to me. Regards to all, interesting discussion.

I just re-read the last paragraph before the word "Compare" and I think that's the Ergo - what, point. Starting with the word "Conclusion" "The gap between U.S. and Canadian spending on health care administration has grown to $752 per capita. A large sum might be saved in the United States if administrative costs could be trimmed by implementing a Canadian-style health care system." Well spoken JB. Nice find, thanks for sharing it.

It's a good point JH. I note that many people who pay the scratch for one of these cams claim that due to the massive range they are perfect as a "when the Sh*t hits the fan" piece....i.e., the piece you grab when you are totally pumped and you MUST get the cam in first try or fly. Although the range on these allows us to think that these are that go-to piece....it's probably the exact wrong time to be utilizing this cam as a plug and fall piece in extreme times. Realistically, I rarely carry mine, mostly preferring not to pay the weight cost and go with a lighter Metolius so that I can have a few extra brownies at night and pad the love handles:-) Mmmmmmm I don't like the extra maintenance needed for these either. I often climb in dirt and dust (Saturday climbing was a vertical dust bowl) and the dust and dirt is anathema to these things working smoothly and effectively.

Whoa, at first I though you were the guy who had posted the purple OP failure on Rockclimbing.com. Linked here I quickly saw you were not. He had tested his purple .5 and it had essentially failed in a placement that a Camalot held. These things have some design characteristics which make certain placements time bombs. Any placement where they can't rotate and take a bit of a sideways force, they seem to be a candidate for failure. There was one placed in am angled pod in JT that surprisingly broke earlier, looking eerily similar to yours except for the color. After that story broke, LINK HERE TO THAT LONG TALE Joseph tried to break one with his hands to make his point that the links and length of the cams lobes are a weak point (he was unsuccessful in that endeavor but you just made his point for him iwth an exclamation mark!). I have the 1 and 2- # 2s and figured I didn't need any more OP cams for this reason. FYI, you can post pics on the fly at CC.com, just click the camera link above and insert the location and the file uploads to CC just like photobucket. Kunza is one of my favorites at Smith, so I know, and want to share the main point with others, that this should have been a low fall factor/low force fall. Cam at the feet but with a lot of rope out and fortunately plenty of placements between you and the deck. I always nut this pitch with 1 cam low on the pitch. Thank you for sharing the story. Any good climbing pics feel free to share those as well. Your cam Of particular note and interest is the Rich Goldstone post on the Cassin Joss cam failure which lead to a fatality on a 5.4/5.5 in the Gunks. I'll quote it slightly modified and with the picture outside of the quote. Here is the failed cam, but click Rgolds link after you read his words as it's a worthwhile read for every climber who would use cams. I like Kates post on the RC.com JT failure thread noted above as well. She said: The resolution of that were the ideas that certain placements like flares, can allow force multipliers and that it's best not to let a sideways hit happen on any Link Cam, or perhaps any cam, if it can't rotate and/or is in a flaring pod or placement. Glad you weren't hurt.

Can you show some pictures and/or let us us know your marking scheme? I have engraved my drivers license #, written my name in black felt tip on others, and used paint in difficult to remove places with my colors of blue and yellow and also posted my rack pics for this very reason. If and when this happens to me, I don't want my stuff to be invisible to my friends in the pawn shops or where ever it ends up. Wishing you a fast and full recovery.....damn that sucks.

No you're not, the real Bobby Jindal isn't as literate or interesting as you normaly are.

This thread needs a gratuitous Jens and Sol climbing pic. Max Hasson photo. http://www.climbing.com/news/hotflashes/beautiful_cascades_testpiece_free-climbed/ edited to make the speling police happy but I got the name correct on the other thread naer naner.

Awesome granite with super pictures!!!! Fing a dudes! Nice. Photo by Max Hasson. Max nailed it.

What just happened here?

...and sniffing the chair Lynn Hill sat on when she came and did her slide show doesn't count ya pervs ......

RIGHT ON gentlemen!!!! I can feel the G*damn heat of that trip just sitting at my desk in an air conditioned office.

WITH directions. The supplement is free as well. Profits from the physical book go towards the area. I think Jeff Wenger should have a link where folks can donate: like Fish has with his "Buy Fish a beer" paypal program, it's nice he puts back in and it would be nice to share that load with him. http://www.lulu.com/content/e-book/trout-creek-climbing-e-book/1936918 Thanks JW. To all as a reminder do not approach from the top down, lead the routes and rap. If yo plan on heading there it's important to take a moment to read the access issues he notes so that the local landowners will stay happy and allow us to continue to climb there.

That is F*ng rad John. However, I noticed that Steve Grossman does that all the time on Supertopo, and it's awesome stuff but the historical stuff just seems to disappear in a flurry of political and religious debates. How about taking the Pirates only forum and making it a History forum? We can maybe get Grossman to post here as well so that the great stuff he digs out of his basement and scans for our enjoyment can be found easy. PS RAINDAWG, WAITING FOR AN ANSWER STILL.