"I suggest going out to the nearest pub and getting completely, and utterly, wasted. Make sure you smoke at least 1 pack of unfiltered Camels. Get the full ashtray, pour a drink in it and then pour the mixture into a water bottle. When you get home (ideally around 3:30am) stick the vile mixture into your freezer. Put on your best gortex and thermal layer. Climb in it. At 5:30am get out, drink (chew?) the mixture and go run the biggest flight of stairs you can find. Run until your heart threatens to explode. Your dehydration caused be the alchohol should adequatlely simulate what you may experience at higher altitudes. Your lung capacity should be sufficiently impaired by the smokes to simulate an oxygen poor enviroment. The freezer episode should adequately replicate a bivy. Drinking the booze/but mixture should simulate your lack of appetite....
Oh - once your finished your workout, go to work (to replicate the long walk out)." - Greg Hamilton