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DirtyHarry

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Everything posted by DirtyHarry

  1. You only need a bag that warm for Alaska or car camping.
  2. Bet it has a nice soothing feel on the skin too when walking.
  3. Either slider alder or devil's club. Its a toss up.
  4. Yeah, looks like fucking rocket science to me. Did you have to ask your advisor for help?
  5. You should go climbing instead.
  6. Once again Gary enlightens all us half-wits with detailed instructions on how to perform the simplest of tasks. Gary, what's next? a photo essay on how to put on pants? Thanks for helping out all us challenged folk though, keep up the good work!
  7. Not recomended, my rockhard abs would only provide uncomfortable seating opportunities.
  8. You can also go down the West Ridge and hike around but it all seems a lot more difficult than just bringing some lightweight aluminums and going down the Sherpa.
  9. Obesity Vaccine Looks Promising -------------------------------------------------------------------------------- Researchers say rats lost 20% to 30% of their body weight while eating normally By Ed Edelson, HealthDay Reporter MONDAY, July 31 (HealthDay News) -- Researchers are reporting progress toward what would be a dream come true for many Americans: a vaccine to prevent obesity. The target of this vaccine is ghrelin, a recently discovered hormone that decreases energy expenditure and fat breakdown. Scientists at the Scripps Research Institute in California reported in this week's issue of the Proceedings of the National Academy of Sciences that they have developed a way to make the immune system produce antibodies that attack ghrelin, and that rats given the vaccine ate normally but lost weight. "We have enabled the immune system to recognize a molecule that it ordinarily won't recognize," explained study author Kim D. Janda, a professor of chemistry at Scripps. The immune system thus produced antibodies that bound to and deactivated ghrelin, just as vaccines against diseases caused by bacteria or viruses bind to and inactivate them. Mice given shots of the vaccine ate just as much as untreated mice but had "about a 20 or 30 percent reduction in weight gain," Janda said. However, the mice were fed low-fat, low-energy diets. It's not certain that a ghrelin vaccine would be effective against the burger-rich, high-fat diet that many Americans eat, the researchers noted. This is not the only effort to develop a vaccine against ghrelin, the Scripps researchers added. Cytos, a Swiss-based biotechnology company, is already testing a different vaccine in humans. It works in a different way than the Scripps vaccine, by preventing the uptake of ghrelin by the brain. A lot of basic work must be done before the Scripps obesity vaccine will be tried in humans, Janda said. "We're going to look at some different flavors of antibodies, see how they work, and then try them in animals," he said. Caution will be the byword, Janda said. "We want to do real basic work and make sure we do all our homework before we look at it in humans," he stressed. "We could do it quickly, but it's prudent to know exactly what's going on." His best guess is that a first human trial is "about two years" away. The Scripps group is looking to link up with a major pharmaceutical company to help develop a usable vaccine, Janda said. It's too early to say how such a vaccine would be given, he said. "It depends on what kind of vaccine it is," Janda said. "It could be given just once or it could be multiple shots." And shots might not even be necessary. There could be an oral vaccine, of the same type as developed for polio and other disease, Janda said. Dr. David E. Cummings, an associate professor of medicine at the University of Washington, did early work showing that ghrelin levels rise before each meal. He said the new study goes a long way toward showing that a ghrelin vaccine could reduce weight gain. The one doubt about ghrelin has been whether its removal would affect weight gain, Cummings said. The weight loss in animals bred to lack the ghrelin gene has been "very subtle," he said, raising doubts about the value of an attack on ghrelin. "The potential value of this study is that it answers the question, 'What if you remove ghrelin from an adult animal?' " Cummings said. "This paper shows that it does affect weight."
  10. And there's atleast one cute girl that works there too.
  11. Only 14 hours of driving? I should just pop over for a short after work sesh.
  12. The weight of the stickers alone must have crushed the one on the right.
  13. In general, climbing the descent route of the most popular alpine gaper route in the state on a weekend is not recomended.
  14. Maybe a 4 after you pull through the steep section where its easier, but the crux is probably 2 or 3 inch.
  15. cams to 3.5". Its essentially a handcrack, but at a real akward angle.
  16. Or even just put up some video cameras in metal cages in the parking lots with signs that say potential thieves - you are being videotaped. Even if the cameras are fake it would be a good deterant.
  17. I remember reading, I think it was in Roper's Camp 4 book, how in the 70's it was fashionable when portaledging on El Cap to have everybody and everything tied into like one shady blade or micronut but then back it all up off a bomber anchor. Perhaps we should all try this just to see what holds and what doesn't.
  18. I think they should let lions, wolves, grizzlies, and elephants roam the streets of Seattle. And killing one with a firearm would be punishable by death.
  19. I don't think this is likely. You would "discover" this mistake as soon as you put weight on the rope. Emily completed the first 10-15 feet of the rappel in full sight of her partner and nothing was noted out of the ordinary. I glanced up and saw her twice as she was coming down - didn't note anything unusual. Let's wait for the final report........... Ok. Sorry for the conjecture. As I understood it, that is what happened in the Snow Creek incident and Montypiton posted that the same thing happened here.
  20. http://msnbc.msn.com/id/8983461/
  21. Nice. We were in there a couple weeks ago. The line you did may be the same as or at least share quite a bit of a route done by Dan Capellini and Erik Snyder a couple years ago.
  22. As has been said here before, with enough speculation, the truth will come out.
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