Sure do. Here's a trip report that I wrote using a modified JavaScript script that I found online. Notice that Opera ignores the "resize=no" command and that somehow Opera thinks images are larger than they are in IE. So the effect is that when using the "open.window" command in JS, the window ends up being a different size from the image, so you can't see all of the pic. But in IE, the window is the same size of the pic, like I specified in the script, and IE doesn't ignore the resize command.
I'll use Opera most of the time, but I'll be resorting to IE for pop-ups like this.