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Ephedra


knotzen

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Well, as jon pointed out, the real hard core athletes do lots of stuff. Maybe this approach will work for you. Take two ephedra, smoke some crack, pull out your teeth, and get on a treadmill. Follow this regimine three times a week at least. When you absolutely must eat, have some horse cock with celery as a palate cleanser. But get right back to the drug/treadmill routine asap.

 

 

Seriously though, working out is the only thing that will help. Not only do you lose a bit of weight, but you feel better and you get stronger. Team sports are great for some folks; I don't like people so the team thing doesn't do it for me. I listen to death metal and lift weights at Gold's--no thrills, no frills. I love it. It's only an hour. I can do anything for an hour a day if it is going to help me climb better, feel better, live better, and increase my chances of getting laid.

Getting started is the hardest. Soon as you are in the habit of going to the gym on a regular basis, you won't even remember what it was like before you started going. That's when you'll have this jewel of a thread to look back on.

Stop reading now and go work out.

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My dad weighed almost 300lbs and he quit drinking, eating crappy food, and went to the gym...all in moderation, and lost 150 lbs. I haven't seem him in years, but he mailed me a photo and i didn't recognize (literally) my own father.

 

Eat less crap.

Eat health food.

Exercise but don't overdue it so you quit.

don't expect anything but better health.

 

My mom weighs like 200 lbs and tried hard-core diets and they never worked.

 

I think i may be adopted.

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-Ephedra? Haven't you ever heard of black coffee? NO sugar NO cream/milk and NO espresso.

 

Earn your sustenance.

-Become addicted to exercise.

-Bike-commute to work, and go for a 30-60 minute fun-paced bike ride or jog before or after work. especially if it is cold out.

-Turn down the heat in your house.

-Eat a HUGE salad, WITHOUT cheese, WITHOUT dressing or oil, before meals. Also works with other vegetables. NO butter either.

-every couple of days, skip breakfast, or skip lunch. I'm serious.

-NEVER, EVER order/buy desert. EVER.

 

This is about who you are. Society has allowed you to become someone with whom you are not satisfied. Do you think people have always had 3+ meals a day, and could just go down to Safeway and purchase 50,000 calories for the equivalent of a couple hours of work? Or go round the corner and grab a 400-calorie Mocha, a 500-calorie scone, and a 1000-calorie chocolate bar on a 15-minute work break? In the modern world food is obtained too easily and for too little. The consequence is a nation that eats too much.

 

And let's not even get started on lack of aerobic exercise. Simply put we'd all be a lot better off (physically) if we still had to hunt down our prey or collect berries for 10 hours in order to get a decent meal. But there's nothing that says we can't still pretend.

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Here are some abstracts from peer-reviewed medical journals to consider.

 

 

Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis.

Shekelle PG - JAMA - 26-MAR-2003; 289(12): 1537-45

From NIH/NLM MEDLINE

Abstract:

CONTEXT: Ephedra and ephedrine sometimes are used for weight loss or enhanced athletic performance, but the efficacy and safety of these compounds are uncertain. OBJECTIVE: To assess the efficacy and safety of ephedra and ephedrine used for weight loss and enhanced athletic performance. DATA SOURCES: We searched 9 databases using the terms ephedra, ephedrine, adverse effect, side effect, efficacy, effective, and toxic. We included unpublished trials and non-English-language documents. Adverse events reported to the US Food and Drug Administration MedWatch program were assessed. STUDY SELECTION: Eligible studies were controlled trials of ephedra or ephedrine used for weight loss or athletic performance and case reports of adverse events associated with such use. Eligible studies for weight loss were human studies with at least 8 weeks of follow-up; and for athletic performance, those having no minimum follow-up. Eligible case reports documented that ephedra or ephedrine was consumed within 24 hours prior to an adverse event or that ephedrine or an associated product was found in blood or urine, and that other potential causes had been excluded. Of the 530 articles screened, 52 controlled trials and 65 case reports were included in the adverse events analysis. Of more than 18 000 other case reports screened, 284 underwent detailed review. DATA EXTRACTION: Two reviewers independently identified trials of efficacy and safety of ephedra and ephedrine on weight loss or athletic performance; disagreements were resolved by consensus. Case reports were reviewed with explicit and implicit methods. DATA SYNTHESIS: No weight loss trials assessed duration of treatment greater than 6 months. Pooled results for trials comparing placebo with ephedrine (n = 5), ephedrine and caffeine (n = 12), ephedra (n = 1), and ephedra and herbs containing caffeine (n = 4) yielded estimates of weight loss (more than placebo) of 0.6 (95% confidence interval, 0.2-1.0), 1.0 (0.7-1.3), 0.8 (0.4-1.2), and 1.0 (0.6-1.3) kg/mo, respectively. Sensitivity analyses did not substantially alter the latter 3 results. No trials of ephedra and athletic performance were found; 7 trials of ephedrine were too heterogeneous to synthesize. Safety data from 50 trials yielded estimates of 2.2- to 3.6-fold increases in odds of psychiatric, autonomic, or gastrointestinal symptoms, and heart palpitations. Data are insufficient to draw conclusions about adverse events occurring at a rate less than 1.0 per thousand. The majority of case reports are insufficiently documented to allow meaningful assessment. CONCLUSIONS: Ephedrine and ephedra promote modest short-term weight loss (approximately 0.9 kg/mo more than placebo) in clinical trials. There are no data regarding long-term weight loss, and evidence to support use of ephedra for athletic performance is insufficient. Use of ephedra or ephedrine and caffeine is associated with increased risk of psychiatric, autonomic, or gastrointestinal symptoms, and heart palpitations.

 

Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine.

Samenuk D - Mayo Clin Proc - 01-JAN-2002; 77(1): 12-6

From NIH/NLM MEDLINE

Abstract:

OBJECTIVE: To evaluate possible cardiovascular toxic effects associated with use of dietary supplements containing ma huang, an herbal source of ephedrine. METHODS: We reviewed the comprehensive database Adverse Reaction Monitoring System of the Food and Drug Administration, which included clinical records, investigative reports, and autopsy reports related to ma huang use. The main outcome measurements were stroke, myocardial infarction, and sudden death. RESULTS: From 1995 to 1997, 926 cases of possible ma huang toxicity were reported to the Food and Drug Administration. In 37 patients (23 women and 14 men with a mean +/- SD age of 43 +/- 13 years), use of ma huang was temporally related to stroke (in 16), myocardial infarction (in 10), or sudden death (in 11). Autopsies performed in 7 of the 11 patients who experienced sudden death showed a normal heart in 1, coronary atherosclerosis in 3, and cardiomyopathies in 3. In 36 of the 37 patients, use of ma huang was reported to be within the manufacturers' dosing guidelines. CONCLUSIONS: Analysis of the 37 patients indicates the following findings: (1) ma huang use is temporally related to stroke, myocardial infarction, and sudden death; (2) underlying heart or vascular disease is not a prerequisite for ma huang-related adverse events; and (3) the cardiovascular toxic effects associated with ma huang were not limited to massive doses. Although the pathogenesis of the cardiac toxic effects of ma huang remains incompletely defined, available observational and circumstantial evidence indicates that use of the substance may be associated with serious medical complications.

 

Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids.

Haller CA - N Engl J Med - 21-DEC-2000; 343(25): 1833-8

From NIH/NLM MEDLINE

Abstract:

BACKGROUND: Dietary supplements that contain ephedra alkaloids (sometimes called ma huang) are widely promoted and used in the United States as a means of losing weight and increasing energy. In the light of recently reported adverse events related to use of these products, the Food and Drug Administration (FDA) has proposed limits on the dose and duration of use of such supplements. The FDA requested an independent review of reports of adverse events related to the use of supplements that contained ephedra alkaloids to assess causation and to estimate the level of risk the use of these supplements poses to consumers. METHODS: We reviewed 140 reports of adverse events related to the use of dietary supplements containing ephedra alkaloids that were submitted to the FDA between June 1, 1997, and March 31, 1999. A standardized rating system for assessing causation was applied to each adverse event. RESULTS: Thirty-one percent of cases were considered to be definitely or probably related to the use of supplements containing ephedra alkaloids, and 31 percent were deemed to be possibly related. Among the adverse events that were deemed definitely, probably, or possibly related to the use of supplements containing ephedra alkaloids, 47 percent involved cardiovascular symptoms and 18 percent involved the central nervous system. Hypertension was the single most frequent adverse effect (17 reports), followed by palpitations, tachycardia, or both (13); stroke (10); and seizures (7). Ten events resulted in death, and 13 events produced permanent disability, representing 26 percent of the definite, probable, and possible cases. CONCLUSIONS: The use of dietary supplements that contain ephedra alkaloids may pose a health risk to some persons. These findings indicate the need for a better understanding of individual susceptibility to the adverse effects of such dietary supplements.

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-Ephedra? Haven't you ever heard of black coffee? NO sugar NO cream/milk and NO espresso.

 

Earn your sustenance.

-Become addicted to exercise.

-Bike-commute to work, and go for a 30-60 minute fun-paced bike ride or jog before or after work. especially if it is cold out.

-Turn down the heat in your house.

-Eat a HUGE salad, WITHOUT cheese, WITHOUT dressing or oil, before meals. Also works with other vegetables. NO butter either.

-every couple of days, skip breakfast, or skip lunch. I'm serious.

-NEVER, EVER order/buy desert. EVER.

 

This is about who you are. Society has allowed you to become someone with whom you are not satisfied. Do you think people have always had 3+ meals a day, and could just go down to Safeway and purchase 50,000 calories for the equivalent of a couple hours of work? Or go round the corner and grab a 400-calorie Mocha, a 500-calorie scone, and a 1000-calorie chocolate bar on a 15-minute work break? In the modern world food is obtained too easily and for too little. The consequence is a nation that eats too much.

 

And let's not even get started on lack of aerobic exercise. Simply put we'd all be a lot better off (physically) if we still had to hunt down our prey or collect berries for 10 hours in order to get a decent meal. But there's nothing that says we can't still pretend.

 

DAMN, now that's putting it well! thumbs_up.gif

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Simply put we'd all be a lot better off (physically) if we still had to hunt down our prey or collect berries for 10 hours in order to get a decent meal. But there's nothing that says we can't still pretend.

 

Actually, hunter-gatherer societies have the greatest amount of leisure time of any human society.

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-Ephedra? Haven't you ever heard of black coffee? NO sugar NO cream/milk and NO espresso.

 

Earn your sustenance.

-Become addicted to exercise.

-Bike-commute to work, and go for a 30-60 minute fun-paced bike ride or jog before or after work. especially if it is cold out.

-Turn down the heat in your house.

-Eat a HUGE salad, WITHOUT cheese, WITHOUT dressing or oil, before meals. Also works with other vegetables. NO butter either.

-every couple of days, skip breakfast, or skip lunch. I'm serious.

-NEVER, EVER order/buy desert. EVER.

 

This is about who you are. Society has allowed you to become someone with whom you are not satisfied. Do you think people have always had 3+ meals a day, and could just go down to Safeway and purchase 50,000 calories for the equivalent of a couple hours of work? Or go round the corner and grab a 400-calorie Mocha, a 500-calorie scone, and a 1000-calorie chocolate bar on a 15-minute work break? In the modern world food is obtained too easily and for too little. The consequence is a nation that eats too much.

 

And let's not even get started on lack of aerobic exercise. Simply put we'd all be a lot better off (physically) if we still had to hunt down our prey or collect berries for 10 hours in order to get a decent meal. But there's nothing that says we can't still pretend.

 

DAMN, now that's putting it well! thumbs_up.gif

 

I want a 1000 calorie candy bar. Where do I get one of these?

And all this time I have been settling for the 300+ ones...

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