I witnessed a pretty funny 'takeoff with somebody on the throne' recently. There was a runway hold, and we were told that it would be 20 minutes or more before we were cleared for takeoff. Meanwhile, a lady's got to go baaad, apparently...must've been coffee kicking in. So the flight attendent says it's okay. Of course, we roar into a takeoff soon after she goes into the head. This poor lady opens the door while sitting and yells "what do I do?!," the flight attendent's yelling"stay put" and pushing on the door...